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1.
Journal of Pharmaceutical Negative Results ; 13:3254-3265, 2022.
Article in English | EMBASE | ID: covidwho-2206768

ABSTRACT

In this study Evaluation of the Prevalence of Heart Problems in Patients with Covid-19 with High Blood Pressure and Diabetes in Patients Admitted to ICU was investigated. Due to the small number of some underlying diseases such as asthma, acute respiratory disease, liver, kidney and cancer, these diseases were merged together and entered as a variable. According to the results of univariate logistic regression, body mass index, diabetes and underlying diseases were related to contracting the Covid-19 disease, so that an increase of one unit of body mass index was 4% and diabetes and underlying diseases also had a 41% chance. It increased the incidence of Covid-19. All variables were entered into the multivariable regression model by enter method to calculate their simultaneous effect. Collinearity between quantitative variables was checked and rejected. After entering the variables into the multivariable logistic regression and observing the effect of each variable in the presence of other variables, almost the same results as the univariate regression were obtained. The results of the present study showed that the risk of hospitalization due to Covid-19 disease is significantly related to male gender and old age, because increasing age leads to defects in the body's immune system's response to pathogens and increases the rate of hospitalization. Also, the current research showed that blacks, obese people and smokers, as well as people with underlying diseases such as diabetes, cardiovascular diseases, kidney and high blood pressure, have the highest number of hospitalizations due to Covid-19. They are because the efficiency of the immune system response in these people is low, so it leads to severe type of disease and hospitalization. Many signs and symptoms in the elderly appear atypical or unusual. Copyright © 2022 Wolters Kluwer Medknow Publications. All rights reserved.

2.
Journal of Pharmaceutical Negative Results ; 13:3239-3253, 2022.
Article in English | EMBASE | ID: covidwho-2206767

ABSTRACT

Covid-19 has broken all records in the field of infectious and pandemic diseases. Both in terms of the number of infected and deaths, and in terms of the geographical extent and depth of the conflict and the damage it inflicts on the body of different countries in the world. This virus was not taken seriously at first and this was the beginning of all the adventures that have involved the world in these few months. Every day, researchers make new findings about Corona, and in some cases, these findings are miles away from what we thought. In the difficult situation that the whole world is struggling with, along with the knowledge and efforts of experts and researchers, the serious determination of people to help break the transmission chain is very important and vital. Although there are notable exceptions, most evidence suggests that the risk of Covid-19 is much lower for children than for adults. Knowing the symptoms of corona in children can help parents and nurses to recognize the emergency warning signs and seek appropriate treatment. This article covers the symptoms of the corona virus in children, some possible complications and when to see a pediatrician. Data collected from China and the United States on children infected with SARS-CoV-2, the virus that causes Covid-19, suggests that the risk of severe disease in children is lower than in adults. According to a study of 2752 children infected with Covid-19, only three died, and the main cause of death in each case is being investigated. Recent evidence suggests that hospitalization rates are higher among infants and some require treatment in the intensive care unit. More than 90% of children in China did not have any symptoms after contracting the corona virus and suffered from a mild illness. Copyright © 2022 Wolters Kluwer Medknow Publications. All rights reserved.

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